ABSTRACT

Natural cyclic compounds have attracted more attention for
several pharmacological applications.
Pyridine and pyrazole activities can be augmented through the
formation of heterocyclic compounds. In this study, we synthesized and
evaluated novel heterocyclic compounds containing pyridine and
pyrazole. The phys- iochemical characteristics revealed the structural
properties of the synthesized compounds. The compounds were
evaluated for their antibacterial and antifungal activities, which showed
significant antimicrobial proper- ties. The antioxidant activities
analyzed by DPPH free radical scavenging activity that showed
concentration dependent scavenging activities of the synthesized
pyridine and pyrazole compounds. These results revealed that the
synthesized compounds could be further evaluated for preparing lead
antimicrobial and antioxidant phar- maceutical agent.
Key words: Pyridine, Pyrazole, Antimicrobial, Antioxidant
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